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What should I watch for while using Estrace?

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Estrace can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your doctor or health care professional if you feel you are retaining fluid.

If you have any reason to think you are pregnant, stop taking Estrace right away and contact your doctor or health care professional.

Smoking increases the risk of getting a blood clot or having a stroke while you are taking Estrace, especially if you are more than 35 years old. You are strongly advised not to smoke.

If you wear contact lenses and notice visual changes, or if the lenses begin to feel uncomfortable, consult your eye doctor or health care professional.

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